New Data on Glucose-6-Phosphate Dehydrogenase Deficiency in Saudi Arabia

Abstract

67/369 male Saudi subjects (18%) were found to be G6PD deficient on screening, and electrophoresis of blood samples stored on filter paper strips revealed B-like variants with intermediate enzyme activity in 11%, presumed Mediterranean variant in 13%, Gd+ (A+) in 2%, Gd–(A–7) in 0.8%, and indeterminate enzyme status in 6% of the subjects tested. A significant association between G6PD deficiency and hemoglobin S correlated with previous studies on similar samples from the same general population.