Effect of Diet on Obesity of Yellow Mice in Inbred Lines.

Abstract

The observation has been confirmed that yellow mice on continued inbreeding no longer become obese if maintained under the usual laboratory conditions. Feeding diets of the "synthetic" type, high in fat, made it possible to induce obesity in the yellow mice but not in their non-yellow littermates. The obese yellow mice were observed to have fatty livers. Two of these animals were found to have liver tumors.