THE EFFECT OF SALICYLATES ON THE ELECTROLYTE STRUCTURE OF THE BLOOD PLASMA. II. THE ACTION OF THERAPEUTIC DOSES OF SODIUM SALICYLATE AND OF ACETYLSALICYLIC ACID IN MAN1
Open Access
- 1 September 1945
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 24 (5), 770-774
- https://doi.org/10.1172/jci101662
Abstract
In the plasma of patients receiving therapeutic doses of Na salicylate or of acetylsalicylic acid decreased tension and content of CO2 and small changes of pH were found. The plasma Cl+ was usually elevated, and the Na was occasionally decreased. The effect of salicylate appeared to be proportional to the dose administered and to increase with the period of medication. The results indicate that salicylates produce primary hyperpnea.This publication has 2 references indexed in Scilit:
- THE EFFECT OF SALICYLATES ON THE ELECTROLYTE STRUCTURE OF THE BLOOD PLASMA. I. RESPIRATORY ALKALOSIS IN MONKEYS AND DOGS AFTER SODIUM AND METHYL SALICYLATE; THE INFLUENCE OF HYPNOTIC DRUGS AND OF SODIUM BICARBONATE ON SALICYLATE POISONING1JCI Insight, 1945
- ACTIONS AND USES OF THE SALICYLATES AND CINCHOPHEN IN MEDICINEMedicine, 1926