Quantification of dextromethorphan and metabolites: a dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity
- 29 March 1996
- journal article
- Published by Elsevier in Journal of Chromatography B: Biomedical Sciences and Applications
- Vol. 678 (1), 105-111
- https://doi.org/10.1016/0378-4347(95)00431-9
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Noninvasive tests of CYP3A enzymesPharmacogenetics, 1994
- Characterization of dextromethorphan N-demethylation by human liver microsomes: Contribution of the cytochrome P450 3A (CYP3A) subfamilyBiochemical Pharmacology, 1994
- The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and NomenclatureDNA and Cell Biology, 1993
- Simultaneous Determination of Dextromethorphan and Three Metabolites in Plasma and Urine Using High-Performance Liquid Chromatography with Application to Their Disposition in ManTherapeutic Drug Monitoring, 1990
- The increase in urinary excretion of 6 beta‐hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.British Journal of Clinical Pharmacology, 1989
- Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients.Journal of Clinical Investigation, 1989
- Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylationClinical Pharmacology & Therapeutics, 1985
- Variability in nifedipine pharmacokinetics and dynamics: A new oxidation polymorphism in manBiochemical Pharmacology, 1984
- Quantitative Determination of Dextromethorphan and Three Metabolites in Urine by Reverse-Phase High-Performance Liquid ChromatographyJournal of Pharmaceutical Sciences, 1984
- Inter-individual variation in the metabolism of dextromethorphanInternational Journal of Pharmaceutics, 1983