Comparative in vitro antibacterial activity of the new carbapenem meropenem (SM-7338)
- 1 December 1989
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Microbiology & Infectious Diseases
- Vol. 8 (12), 1061-1064
- https://doi.org/10.1007/bf01975170
Abstract
The in vitro antimicrobial activity of the new carbapenem meropenem (SM-7338) was determined by an agar dilution method in comparison with imipenem, ticarcillin/calvulanic acid, ceftazidime and the fourth-generation cephalosporin cefepime (BMY 28142). Meropenem showed superior activity againstEnterobacteriaceae (MIC90≤0.06 mg/l) and against non-fermentative gram-negative rods, with the exception ofXanthomonas maltophilia. Meropenem had excellent activity against beta-lactamase-producingHaemophilus influenzae andNeisseria gonorrhoeae, and against theBacteroides fragilis group. Imipenem was slightly more active then meropenem against gram-positive cocci especiallyEnterococcus faecalis.This publication has 4 references indexed in Scilit:
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