The discovery of insulin has centered the attention of investigators and clinicians on the treatment of abnormal carbohydrate metabolism somewhat to the exclusion of further refinements in the diagnosis of this condition. The work of Sherrill1brings out the importance of early diagnosis and shows how this may be accomplished through the use of the alimentary glucose tolerance test in obesity and in the families of diabetic patients. John2points out that, making allowance for such border-line conditions as renal glycosuria, toxic and infectious states and endocrine disorders, the simple glucose test reveals many early and latent cases of diabetes in which prophylactic measures are of value. Olmsted and Gay3emphasize all the various factors concerned in the duration of hyperglycemia after the standardized Janney glucose tolerance meal and the fact that each of these should be considered in the interpretation of blood glucose curves. Rigler and