Genetic Aspects of Rett Syndrome
- 1 January 1988
- journal article
- review article
- Published by SAGE Publications in Journal of Child Neurology
- Vol. 3 (1_suppl), S76-S78
- https://doi.org/10.1177/0883073888003001s15
Abstract
To date over 1,000 cases of Rett syndrome have been described in females exclusively. Some of these cases, less than 2 in 100, are familial. The inheritance through maternal lines in the familial cases suggests that Rett syndrome is an X-linked disorder lethal in males. Hypotheses about the genetic mechanisms involved in this syndrome along with suggestions to approach the molecular basis of this disorder are presented. (J Child Neurol 1988;3(Suppl):S76-S78).Keywords
This publication has 2 references indexed in Scilit:
- Linkage analysis of the Rett syndrome using human chromosomal specific probesBrain & Development, 1985
- INHERITANCE OF BALDNESSJournal of Heredity, 1916