Abstract
To the Editor: Sexual contact, whether heterosexual or homosexual, is the most important mode of transmission of the human immunodeficiency virus (HIV) throughout the world.1 Epidemiologic data, combined with the finding of HIV in seminal fluid, cervical secretions, and blood, provide a theoretical basis for the recommendation by the U.S. Public Health Service that use of condoms by homosexuals or heterosexuals may offer protection against HIV transmission.2 A recent report presented experimental evidence that despite mechanical stresses, condoms provide an effective barrier against HIV.3 We report epidemiologic evidence that condoms may reduce the risk of HIV acquisition through sexual intercourse. . . .

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