Adenosine Deaminase in the Diagnosis of Pleural Effusions
- 12 January 1984
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 215 (4), 299-304
- https://doi.org/10.1111/j.0954-6820.1984.tb05011.x
Abstract
The activity of adenosine deaminase (ADA) was determined in serum and pleural fluid of 90 patients with pleural effusions of various etiology. Tuberculous pleural effusions, empyemas and rheumatoid pleural effusions demonstrated significantly higher activities of ADA than parapneumonic, nonspecific and malignant pleural effusions and effusions in systemic lupus erythematosus and congestive heart failure. In tuberculosis, empyema and rheumatoid arthritis ADA activity was significantly higher in pleural fluid than in serum, indicating a local synthesis of ADA by cells within the pleural cavity in these diseases.Keywords
This publication has 21 references indexed in Scilit:
- Beta2Microglobulin in Pleural EffusionsActa Medica Scandinavica, 1982
- Pleural fluid lysozyme in human diseaseArchives of Internal Medicine, 1979
- Adenosine deaminase activity in pleural effusions: an aid to differential diagnosis.BMJ, 1978
- A role for adenosine deaminase in human monocyte maturation.JCI Insight, 1976
- Tuberculous PleurisyChest, 1973
- ADENOSINE-DEAMINASE DEFICIENCY IN TWO PATIENTS WITH SEVERELY IMPAIRED CELLULAR IMMUNITYThe Lancet, 1972
- Rheumatoid pleuritis.Annals Of The Rheumatic Diseases, 1967
- Serum Adenosine Deaminase in the Differential Diagnosis of JaundiceBMJ, 1965
- PLEURAL BIOPSY IN THE DIAGNOSIS OF PLEURAL EFFUSION A REPORT OF 200 CASES*1The Lancet, 1958
- Pleural EffusionNew England Journal of Medicine, 1955