Platelet Function

Abstract

Basic knowledge regarding platelet physiology was reviewed and related to clinical situations where platelet function is critically important. Platelet function tests such as aggregation and survival studies may soon be available to aid in the diagnosis and management of clinical bleeding problems. A growing understanding of drug-platelet interaction allows manipulation of platelets and the clotting system to improve the prognoses for patients with thromboembolic diseases. Advances in platelet storage and transfusion techniques can save patients who previously might have bled to death. Proper application of the new developments in cardiopulmonary bypass and hemodilution, with attention to platelet and coagulation factor preservation, contributes to securing hemostasis and conserving blood products.