Blank1 recently reported on the relative effectiveness of a lotion containing 0.01% triamcinolone acetonide compared to 1% hydrocortisone in 30 patients with atopic or seborrheic dermatitis. He and his co-workers found that in 28 of 30 patients the 0.01% triamcinolone was as effective or more effective than the 1% hydrocortisone, that is, in 10 of 30 the 0.01% triamcinolone was superior; in 18 of 30 the lotions were equally effective. Consequently, we sought further information on the subject. Method and Materials This study comprised 40 outpatients with various dermatoses: atopic dermatitis, 28; contact dermatitis, 5; lichen simplex chronicus, 2; numular eczema, 2; autoeczematization, 1; erythema multiforme, 1; and pityriasis rosea, 1. Each patient had bilateral symmetrical lesions so that a paired symmetrical comparison of the 2 creams could be done. The side of application of a particular cream was varied with successive patients so that no right or left