A gene required for the specification of dorsal-ventral pattern in Drosophila appears to encode a serine protease
- 1 October 1986
- journal article
- Published by Springer Nature in Nature
- Vol. 323 (6090), 688-692
- https://doi.org/10.1038/323688a0
Abstract
The maternal effect gene snake is required for the establishment of the dorsal-ventral axis during the embryonic development of Drosophila. The molecular cloning of the gene and analysis of a complementary DNA sequence suggest that the gene encodes a serine protease which is structurally similar to proteases involved in blood clotting, peptide processing, and complement fixation pathwaysKeywords
This publication has 26 references indexed in Scilit:
- Establishment of dorsal-ventral polarity in the drosophila embryo: The induction of polarity by the Toll gene productCell, 1985
- Isolation and Structural Analysis of the extra sex combs Gene of DrosophilaCold Spring Harbor Symposia on Quantitative Biology, 1985
- Information for the dorsal–ventral pattern of the Drosophila embryo is stored as maternal mRNANature, 1984
- Vectors for P element-mediated gene transfer inDrosophilaNucleic Acids Research, 1983
- Chromosomal walking and jumping to isolate DNA from the Ace and rosy loci and the bithorax complex in Drosophila melanogasterJournal of Molecular Biology, 1983
- Method to determine the reading frame of a protein from the purine/pyrimidine genome sequence and its possible evolutionary justification.Proceedings of the National Academy of Sciences, 1981
- Mutations affecting segment number and polarity in DrosophilaNature, 1980
- Covalent structure of human haptoglobin: a serine protease homolog.Proceedings of the National Academy of Sciences, 1980
- Serine Proteases: Structure and Mechanism of CatalysisAnnual Review of Biochemistry, 1977
- A Family of Protein-Cutting ProteinsScientific American, 1974