THE INFLUENCE OF THE KAPPA-AGONIST BREMAZOCINE ON INGESTIVE BEHAVIOR IN MICE AND RATS
- 1 January 1983
- journal article
- research article
- Vol. 262 (1), 4-12
Abstract
The effects of bremazocine on drinking and eating behavior were studied in non-deprived mice and 12 h food and water deprived rats. In both species, bremazocine (1-8 mg/kg) produced substantial increases in fluid intake (dose-dependent in rats). The concomitant alterations of food intake were less pronounced and opposite i.e., increase in mice, decrease in rats. Morphine (1.25-10.0 mg/kg) invariably inhibited eating and drinking behavior in mice. The effects of the .kappa.-receptor agonist bremazocine are not affected by naloxone which attenuates the effects of the .mu.-receptor agonist morphine.This publication has 7 references indexed in Scilit:
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