A mitochondrial frameshift-suppressor (+) of the yeast S. cerevisiae maps in the mitochondrial 15S rRNA locus
- 1 January 1987
- journal article
- research article
- Published by Springer Nature in Current Genetics
- Vol. 11 (4), 295-301
- https://doi.org/10.1007/bf00355403
Abstract
The first case of a +1 “extrageneic” frameshift suppressor (MF1), mapping in the yeast mitochondrial 15S rRNA gene is reported. The suppressor was identified by genetic analyses in a leaky mitochondrial oxi1 frameshift mutant and the respective wild-type strain 777-3A of the yeast S. cerevisiae. This is in accordance with the finding that all mitochondrial frameshift mutants isolated from this strain tend to be leaky to a variable degree. MF1 does not suppress known nonsense mutations created by a direct basepair exchange in strain 777-3A. These mutants exhibit a non-leaky phenotype (Weiss-Brummer et al. 1984).Keywords
This publication has 32 references indexed in Scilit:
- Codon reading patterns in Saccharomyces cerevisiae mitochondria based on sequences of mitochondrial tRNAsFEBS Letters, 1986
- Expression of the Rous Sarcoma Virus pol Gene by Ribosomal FrameshiftingScience, 1985
- Complete nucleotide sequence of bacteriophage T7 DNA and the locations of T7 genetic elementsJournal of Molecular Biology, 1983
- Read-through translationTrends in Biochemical Sciences, 1983
- Secondary Structure of 16 S Ribosomal RNAScience, 1981
- Leaky +1 and −1 frameshift mutations at the same site in a yeast mitochondrial geneNature, 1980
- Genetic and physical analysis of the mitochondrial gene for subunit II of yeast cytochrome c oxidaseJournal of Molecular Biology, 1979
- The Mitochondrial COB Region in Yeast Codes for Apocytochrome b and Is MosaicEuropean Journal of Biochemistry, 1979
- Antimycin resistance in saccharomyces cerevisiae: a new mutation on the mitDNA conferring antimycin resistance on the mitchondrial respiratory chainBiochemical and Biophysical Research Communications, 1976
- Biochemical Genetics of Oxidative PhosphorylationScience, 1967