Cancer chemoprevention with dietary phytochemicals
Top Cited Papers
- 1 December 2003
- journal article
- review article
- Published by Springer Nature in Nature Reviews Cancer
- Vol. 3 (10), 768-780
- https://doi.org/10.1038/nrc1189
Abstract
Chemoprevention refers to the use of agents to inhibit, reverse or retard tumorigenesis. Numerous phytochemicals derived from edible plants have been reported to interfere with a specific stage of the carcinogenic process. Many mechanisms have been shown to account for the anticarcinogenic actions of dietary constituents, but attention has recently been focused on intracellular-signalling cascades as common molecular targets for various chemopreventive phytochemicals.Keywords
This publication has 117 references indexed in Scilit:
- Curcumin alters EpRE and AP‐1 binding complexes and elevates glutamate‐cysteine ligase gene expressionThe FASEB Journal, 2003
- Cancer prevention – the potential for diet to modulate molecular signallingTrends in Molecular Medicine, 2003
- Response of Apcmin and A33ΔNβ-cat mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)Mutation Research, 2002
- Inhibition of β-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H2O2 at physiologically relevant EGCG concentrationsBiochemical and Biophysical Research Communications, 2002
- Regulation of Constitutive and Induced NF-κB Activation in Malignant Melanoma Cells by Capsaicin Modulates Interleukin-8 Production and Cell ProliferationJournal of Interferon & Cytokine Research, 2002
- The multifaceted roles of glycogen synthase kinase 3β in cellular signalingProgress in Neurobiology, 2001
- Capsaicin suppresses phorbol ester-induced activation of NF-κB/Rel and AP-1 transcription factors in mouse epidermisCancer Letters, 2001
- Relationship of β-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min miceCarcinogenesis: Integrative Cancer Research, 1999
- Chemoprevention of CancerScientific American, 1996
- Capsaicin, a double-edged sword: Toxicity, metabolism, and chemopreventive potentialLife Sciences, 1995