Effects of Verapamil – a Calcium Inhibitor – on the Vasomotor Response of Cortical and Juxtamedullary Glomeruli of the Human Kidney

Abstract
Cortical and juxtamedullary glomeruli of the human kidney were isolated by sieving. Verapamil, a calcium inhibitor, was added to a suspension of the glomeruli. The vasomotor response was measured by a video analyser. We were thus able to determine the modiñcation of the cortical and juxtamedullary glomeruli surface area. Only the cortical glomeruli became vasodilated in response to the calcium inhibitor.