Ehlers-Danlos Syndrome. Presented by Dr. Frances Pascher and (by invitation) Dr. Abram Kanof. P. G., a white boy aged 5 years, was admitted to the pediatric ward of the Jewish Sanitarium and Hospital for Chronic Diseases, of Brooklyn, because of weakness and hypermobility of the joints since birth. There is no parental consanguinity. The father and a cousin are known to be ``double-jointed.'' Examination reveals dermatorrhexis, dermatochalasis, and arthrochalasis. The skin of any part of the body can be stretched 8 to 10 cm., snapping back promptly when released. The integument has a soft pleasant feel, bruises readily, with the development of ecchymoses, and shows a few papyrus-like scars over the knees. The tourniquet test is strongly positive, and ecchymosis after drawing blood for analysis is tremendous. The general looseness and hypermobility of all the joints is striking, occurring to the extent that the hips are both dislocated and