Differentiation of a rat mammary cell line in vitro.
- 1 March 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (3), 1256-1260
- https://doi.org/10.1073/pnas.76.3.1256
Abstract
The development of fusiform (probably related to myoepithelial) cells was studied in Rama 25 [rat mammary cancer] cultures. They are generated from special differentiated structures (projections) that contain a rapidly differentiating cell type (F-precursor cells). Clonal sublines isolated from projections develop in several directions under both environmental and genetic control. Some types of differentiation are reversible; others are irreversible. The various cell types occurring in vitro may correspond to specific cell types in vivo.Keywords
This publication has 21 references indexed in Scilit:
- Thy-1: a differentiation marker of potential mammary myoepithelial cells in vitro.Proceedings of the National Academy of Sciences, 1978
- A possible mammary stem cell lineCell, 1978
- Histopathogenesis of 7,12-diemthylbenz(a)anthracene-induced rat mammary tumors.Proceedings of the National Academy of Sciences, 1977
- ALPHA-LACTALBUMIN CONTENT OF RAT MAMMARY CARCINOMAS AND EFFECT OF PITUITARY STIMULATION1977
- MEASUREMENT OF ALPHA-LACTALBUMIN IN SERUM AND MAMMARY-TUMORS OF RATS BY RADIOIMMUNOASSAY1977
- Production of specific antibodies to contractile proteins, and their use in immunofluorescence microscopyHistochemistry and Cell Biology, 1977
- The effect of very frequent milking and of oxytocin on the yield and composition of milk in fed and fasted goatsThe Journal of Physiology, 1967
- The Variation in the Composition of Milk During Successive Stages of Milk Removal from the Mammary Gland of the CowAustralian Journal of Biological Sciences, 1965
- Cultivation and properties of bovine mammary cell culturesExperimental Cell Research, 1961
- Cultivation and behavior in vitro of the normal mammary epithelium of the adult mouseThe Anatomical Record, 1957