Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor
- 16 April 2007
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 5 (10), 1562-1568
- https://doi.org/10.1039/b703033a
Abstract
The use of three orthogonally tagged phosphine reagents to assist chemical work-up via phase-switch scavenging in conjunction with a modular flow reactor is described. These techniques (acidic, basic and Click chemistry) are used to prepare various amides and tri-substituted guanidines from in situ generated iminophosphoranes.Keywords
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