Reaction of OH Radicals with Nucleic Acid Bases—An E.S.R. Study
- 1 January 1966
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 10 (6), 533-538
- https://doi.org/10.1080/09553006614550631
Abstract
The reactions of OH radicals with nucleic acid bases have been studied in aqueous solutions at pH 1 using electron-spin-resonance spectroscopy. It was found that the pyrimidine bases were more reactive than the purines and free radical products could only be detected in the pyrimidines. In thymine, cytosine and uracil, the OH radical added to the 5, 6 double bond. This confirms the conclusions of previous radiation chemical studies by other authors.This publication has 8 references indexed in Scilit:
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