Breast-Cancer Prognosis and Ovarian Cortical Stromal Hyperplasia

Abstract

THE relation between hyperplasia of the stroma of the ovarian cortex and cancer in the human female was first indicated by Smith¹ in his review of endometrial cancer. Subsequently, Woll and his co-workers² reported its occurrence in the ovaries of 84 per cent of 331 patients with endometrial cancer. Sommers and Teloh³ showed an association in cases of carcinoma of the human female breast. At autopsy they found cortical stromal hyperplasia in the ovaries of 83 of 100 women with cancer of the breast, as opposed to an incidence of 37.5 per cent in a control group.In cases of . . .