Severe Aplastic Anaemia with Complete Autologous Marrow Reconstitution Following Treatment with Antithymocyte Globulin
- 1 July 1978
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Haematology
- Vol. 21 (1), 14-18
- https://doi.org/10.1111/j.1600-0609.1978.tb02489.x
Abstract
In a patient with end-stage acquired aplastic anemia, unsuccessful treatment with splenectomy, prednisone, pyridoxine and anabolic steroid was followed by administration of antithymocyte globulin (ATG). This therapy soon led to a gradual improvement and after 12 mo. complete remission was obtained. The possible mechanism of action of ATG and the general principles of treatment are discussed.Keywords
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