Multiple local minima in radiotherapy optimization problems with dose–volume constraints
- 1 July 1997
- journal article
- research article
- Published by Wiley in Medical Physics
- Vol. 24 (7), 1157-1161
- https://doi.org/10.1118/1.598017
Abstract
The cause of multiple local minima in beam weight optimization problems subject to dose–volume constraints is analyzed. Three objective functions were considered: (a) maximization of tumor control pr...Keywords
This publication has 12 references indexed in Scilit:
- Comparison of simulated annealing algorithms for conformal therapy treatment planningInternational Journal of Radiation Oncology*Biology*Physics, 1995
- Optimization of intensity-modulated 3D conformal treatment plans based on biological indicesRadiotherapy and Oncology, 1995
- Treatment Optimization Using Physical and Radiobiological Objective FunctionsPublished by Springer Nature ,1995
- The potential and limitations of the inverse radiotherapy techniqueRadiotherapy and Oncology, 1994
- Optimization of beam orientations in radiation therapy: some theoretical considerationsPhysics in Medicine & Biology, 1993
- CCRT for non-small cell lung cancer: Sensitivity of clinical gains to organ tolerance restrictionsInternational Journal of Radiation Oncology*Biology*Physics, 1992
- Random search algorithm (RONSC) for optimization of radiation therapy with both physical and biological end points and constraintsInternational Journal of Radiation Oncology*Biology*Physics, 1992
- Large scale optimization of beam weights under dose-volume restrictionsInternational Journal of Radiation Oncology*Biology*Physics, 1990
- Optimization of beam weights under dose-volume restrictionsInternational Journal of Radiation Oncology*Biology*Physics, 1987
- The Relation Between Tumour Lethal Doses and the Radiosensitivity of Tumour CellsThe British Journal of Radiology, 1961