A controlled clinical trial of alpha methyl dopa in Parkinsonian tremor
- 1 December 1963
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 26 (6), 505-510
- https://doi.org/10.1136/jnnp.26.6.505
Abstract
Alpha methyl dopa given orally in a dose of 1 to 1.5 g/day for one week was effective in diminishing Parkinsonian tremor in the majority of patients treated. The effect on blood pressure was negligible while drowsiness and depression were the main side-effects. These initital observations justify a long-term trial which would be necessary for a final assessment of the drug''s therapeutic usefulness.Keywords
This publication has 8 references indexed in Scilit:
- Effect of alpha methyl dopa on experimental tremorJournal of Neurology, Neurosurgery & Psychiatry, 1963
- The response of normal retinal blood vessels to angiotensin and noradrenalineThe Journal of Physiology, 1963
- A METHOD FOR ASSESSING THE EFFECTS OF DRUGS ON THE CENTRAL ACTIONS OF 5‐HYDROXYTRYPTAMINEBritish Journal of Pharmacology and Chemotherapy, 1963
- The site of origin of the tremor produced by tubocurarine acting from the cerebral ventriclesThe Journal of Physiology, 1962
- Pharmacodynamic effects and clinical use of alpha methyldopa in the treatment of essential hypertension∗The American Journal of Cardiology, 1962
- THE EFFECTS OF ADRENALINE, NORADRENALINE, AND ISOPRENALINE ON PARKINSONIAN TREMORJournal of Neurology, Neurosurgery & Psychiatry, 1962
- On the nature of normal tremorNeurology, 1962
- Action of Adrenaline and Noradrenaline on the Tremor in Parkinson's DiseaseNeurology, 1952