Choline accumulation by photoreceptor cells of the rabbit retina.
- 1 March 1980
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 77 (3), 1671-1675
- https://doi.org/10.1073/pnas.77.3.1671
Abstract
Photoreceptor cells of the rabbit retina accumulate choline from the extracellular environment by an overall process with a high affinity for choline. These cells do not synthesize acetylcholine; the choline is incorporated into phosphorylcholine and eventually phospholipid. A mechanism for efficient choline accumulation is presumably concomitant to the photoreceptor cell''s synthesis of large amounts of membrane for outer segment membrane renewal. Its existence in the photoreceptor cell supports previous evidence that high-affinity choline uptake is not confined to neurons that release acetylcholine, but may be present wherever large amounts of choline are required.This publication has 35 references indexed in Scilit:
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