Amino acids and peptides. XXVI. Phosphorus in organic synthesis. XV. Application of diphenyl phosphorazidate (DPPA) and diethyl phosphorocyanidate (DEPC) to the synthesis of the N-terminal decapeptide of gastric inhibitory polypeptide.
- 1 January 1977
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 25 (2), 224-230
- https://doi.org/10.1248/cpb.25.224
Abstract
The synthesis of the N-terminal decapeptide of gastric inhibitory polypeptide (GIP) [a gastrointestinal hormone], Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr was carried out in 2 ways (F1 + F2-4 + F5-10 and F1-4 + F5-10) using DPPA and DEPC as coupling reagents.This publication has 2 references indexed in Scilit:
- Amino acids and peptides. XXV. Phosphorus in organic synthesis. XIV. Application of diphenyl phosphorazidate (DPPA) to the vasoactive intestinal peptide.CHEMICAL & PHARMACEUTICAL BULLETIN, 1977
- Phosphorus in organic synthesis—XI Amino acids and peptides—XXITetrahedron, 1976