Adenomatoid tumor: Immunohistological features suggesting a mesothelial origin
- 1 November 1982
- journal article
- research article
- Published by Springer Nature in Virchows Archiv B Cell Pathology Including Molecular Pathology
- Vol. 42 (1), 153-159
- https://doi.org/10.1007/bf02890378
Abstract
Summary Four adenomatoid tumors of the epididymis were evaluated immununohistologically for the expression of intermediate filaments and endothelial cell markers, factor VIII-related antigen and binding of Ulex europaeus I-lectin (UEA I). Immunofluorescence microscopy showed a strong reaction with antikeratin but not with anti-vimentin antibodies, indicating that adenomatoid tumor cells contain epithelial but not mesenchymal type of intermediate filaments. No staining of tumor cells was seen with anti-FVIII-related antigen antibodies or with fluorochrome-coupled UEA I. The results support the mesothelial, non-endothelial origin of adenomatoid tumors.Keywords
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