EFFECT OF THYMINE STARVATION ON CHROMOSOME TRANSFER DURING CONJUGATION IN ESCHERICHIA COLI
- 1 January 1966
- journal article
- research article
- Published by Genetics Society of Japan in The Japanese Journal of Genetics
- Vol. 41 (1), 75-89
- https://doi.org/10.1266/jjg.41.75
Abstract
The effect of thymine starvation on chromosome transfer was examined with special reference to the relationship between transfer and replication, using JG181 and JG185 of Escherichia coli as the genetic donor. Thymine starvation of Hfr cells inhibited chromosome transfer. Uracil and histidine double starvation in Hfr cells protected them from the spontaneous interruption of the process. The inhibitory effect of thymine starvation was differentially active, the more distant from the origin of an Hfr chromosome a given genetic marker was located, the more strongly transfer of that marker was inhibited. This inhibitory effect of thymine starvation was (at least, partially) reversible.Keywords
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