Control of Blood Glucose and Diabetic Vascular Disease

Abstract
Both the method of treating insulin-dependent diabetes and the relation between treatment and vascular complications have become subjects of renewed interest. There has been a long standing impression among many diabetologists that good control of blood glucose may prevent or delay the vascular complications of diabetes, When subjected to critical analysis, however, the various clinical studies attempting to demonstrate a beneficial effect of rigid glucose control have been, at best, inconclusive.1 , 2 Several recent publications have strongly implied that new findings in animals and man support the view that tight glucose regulation has a beneficial effect on diabetic vascular disease. The . . .