Transcatheter aortic valve implantation: current and future approaches
- 15 November 2011
- journal article
- review article
- Published by Springer Nature in Nature Reviews Cardiology
- Vol. 9 (1), 15-29
- https://doi.org/10.1038/nrcardio.2011.164
Abstract
The first human transcatheter aortic valve implantation (TAVI) in 2002, and several subsequent single-center series, showed the feasibility of this new approach for the treatment of patients with severe aortic stenosis who were considered to be at very high or prohibitive surgical risk. More-recent multicenter registries have confirmed the safety and efficacy of this procedure, despite a very-high-risk patient profile. Moreover, the randomized, controlled PARTNER trial has confirmed both the superiority of TAVI over medical treatment in patients not considered to be candidates for standard surgical aortic valve replacement and the noninferiority of TAVI compared with surgical aortic valve replacement in high-risk patients. The hemodynamics of transcatheter valves are usually excellent, although residual paravalvular aortic regurgitation (usually trivial or mild) is frequent. Stroke, major vascular complications, and conduction disturbances leading to permanent pacemaker implantation remain among the most-concerning periprocedural complications of TAVI. Nevertheless, promising preliminary data exist for long-term outcomes following TAVI, 'valve-in-valve' TAVI for surgical prosthesis dysfunction, and for the treatment of lower-risk patients. Improvements in transcatheter valve technology, optimization of procedural and midterm results, and confirmation of long-term durability of transcatheter valve prostheses will determine the expansion of TAVI towards the treatment of a broader spectrum of patients.Keywords
This publication has 131 references indexed in Scilit:
- Quality of life improvement at midterm follow-up after transcatheter aortic valve implantationInternational Journal of Cardiology, 2013
- Long-Term Outcomes After Transcatheter Aortic Valve Implantation in High-Risk Patients With Severe Aortic StenosisJournal of the American College of Cardiology, 2011
- Transcatheter aortic valve implantationCatheterization and Cardiovascular Interventions, 2011
- Clinical outcome and predictors for adverse events after transcatheter aortic valve implantation with the use of different devices and access routesAmerican Heart Journal, 2011
- Incidence and predictors of acute kidney injury in patients undergoing transcatheter aortic valve implantationAmerican Heart Journal, 2011
- Performance-based functional assessment of patients undergoing transcatheter aortic valve implantationAmerican Heart Journal, 2011
- Early and Late (One Year) Outcomes Following Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis (from the United States REVIVAL Trial)The American Journal of Cardiology, 2011
- ESC Working Group on Valvular Heart Disease Position Paper: assessing the risk of interventions in patients with valvular heart diseaseEuropean Heart Journal, 2011
- One year follow-up of the multi-centre European PARTNER transcatheter heart valve studyEuropean Heart Journal, 2010
- Acute kidney injury following transcatheter aortic valve implantation: predictive factors, prognostic value, and comparison with surgical aortic valve replacementEuropean Heart Journal, 2009