The surgical approach to inflammatory lesions of the small intestine is predicated on the type of involvement. Basically there are two types: (1) primary involvement, as is seen in cases of regional enteritis, and (2) secondary inflammatory lesions, as not infrequently follow obstruction of the small intestine or mesenteric thrombosis. Of necessity, this discussion of the surgical aspects of inflammatory lesions of the small intestine will deal principally with regional enteritis which has involved the small bowel alone, and also with inflammation of the terminal ileum which is associated with ulcerative colitis. Mention will be made of 2 instances, from our surgical service, of chronic organizing enteritis, which aptly, I believe, should come under this general topic. The most interesting of all primary lesions of the jejunum and ileum is the so-called terminal ileitis, regional enteritis or segmental enteritis, as has been so vividly and completely described by Crohn, Ginzburg