Neural Context Reinstatement Predicts Memory Misattribution
Open Access
- 15 May 2013
- journal article
- Published by Society for Neuroscience in Journal of Neuroscience
- Vol. 33 (20), 8590-8595
- https://doi.org/10.1523/jneurosci.0096-13.2013
Abstract
What causes new information to be mistakenly attributed to an old experience? Some theories predict that reinstating the context of a prior experience allows new information to be bound to that context, leading to source memory confusion. To examine this prediction, we had human participants study two lists of items (visual objects) on separate days while undergoing functional magnetic resonance imaging. List 1 items were accompanied by a stream of scene images during the intertrial interval, but list 2 items were not. As in prior work by Hupbach et al. (2009), we observed an asymmetric pattern of misattributions on a subsequent source memory test: participants showed a strong tendency to misattribute list 2 items to list 1 but not vice versa. We hypothesized that these memory errors were due to participants reinstating the list 1 context during list 2. To test this hypothesis, we used a pattern classifier to measure scene-related neural activity during list 2 study. Because scenes were visually present during list 1 but not list 2, scene-related activity during list 2 study can be used as a time-varying neural indicator of how much participants were reinstating the list 1 context during list 2 study. In keeping with our hypothesis, we found that prestimulus scene activation during the study of list 2 items was significantly higher for items subsequently misattributed to list 1 than for items subsequently correctly attributed to list 2. We conclude by discussing how these findings relate to theories of memory reconsolidation.Keywords
This publication has 25 references indexed in Scilit:
- Neural Reactivation Reveals Mechanisms for Updating MemoryJournal of Neuroscience, 2012
- Prestimulus theta activity predicts correct source memory retrievalProceedings of the National Academy of Sciences, 2011
- Listening for recollection: a multi-voxel pattern analysis of recognition memory retrieval strategiesFrontiers in Human Neuroscience, 2010
- Recollection, Familiarity, and Cortical Reinstatement: A Multivoxel Pattern AnalysisNeuron, 2009
- Reconsolidation: maintaining memory relevanceTrends in Neurosciences, 2009
- Episodic memory reconsolidation: Updating or source confusion?Memory, 2009
- Multivoxel Pattern Analysis Reveals Increased Memory Targeting and Reduced Use of Retrieved Details during Single-Agenda Source MonitoringJournal of Neuroscience, 2009
- Memory search and the neural representation of contextTrends in Cognitive Sciences, 2008
- Wandering Minds: The Default Network and Stimulus-Independent ThoughtScience, 2007
- Reconsolidation of episodic memories: A subtle reminder triggers integration of new informationLearning & Memory, 2007