Translation of melittin messenger RNA in vitro yields a product terminating with glutaminylglycine rather than with glutaminamide.
- 1 March 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (3), 975-978
- https://doi.org/10.1073/pnas.74.3.975
Abstract
Melittin mRNA from queen bee venom glands was translated in a cell-free system from wheat germ. A product larger than promelittin was formed which had the carboxy-terminal sequence -Gln-Gln-GlyCOOH. Melittin and promelittin from venom glands terminated in -Gln-GlnCONH2. The possible role of the extra glycine residue in the formation of a COOH-terminal amide via a transamidase-like reaction was discussed.This publication has 21 references indexed in Scilit:
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