Cross Immunity Experiments in Monkeys Between Variola, Alastrim and Vaccinia

Abstract

In spite of the voluminous literature, much of it of a polemical rather than scientific nature, on the immunity relationships between variola and vaccinia, comparatively little work has been carried out on experimental animals, and the results of different workers are not altogether concordant. Even in the important article by Blaxall (1930) in the System of Bacteriology only a few lines were devoted to a discussion of the existing experimental evidence, and also in the more recent article by Gastinel (1938) this particular problem has been very briefly treated.