Fluorescence of Adenine and Inosine Nucleotides.

Abstract

Adenine and inosine nucleotides have been shown to exert native fluorescence, although with low quantum yield. The highest quantum yield was obtained with adenine derivatives in acid solution. An attachment of the ribosyl group to adenine increased the fluorescence intensity, but this increase was somewhat quenched by phosphate groups. At neutrality the fluorescence of adenine derivatives was greatly decreased. Inosine nucleotides showed very low fluorescence intensity at any value of pH.