Multiple Gene Loci for the Monomeric Hemoglobin of the Hagfish ( Eptatretus stoutii )

Abstract
The fact that members of the subclass Cyclotomata possess monomeric hemoglobin molecules has been known for some time. Electrophoresis of hemolysates from 12 hagfish (Eptatretus stoutii) revealed five hemoglobin phenotypes with four to six distinct zones of hemoglobin. Each zone is believed to represent a monomer containing one heme group on a single polypeptide chain with a molecular weight of approximately 18,000. It is postulated that these monomers are controlled by genes at four loci.