Über die Darstellung von carcinogenen Aminen aus hydrierbaren Vorstufen und die Stabilität der eingeführten Wasserstoff-Atome gegen Austauschreaktionen

Abstract

The synthesis of carcinogenic amines, such as 2-amino- and 2,7-diamino-fluorene and their corresponding acetates, as well as 4-dimethylaminostilbene, by catalytic hydrogenation of suitable precursors is described. The reactions are proposed for the introduction of tritum into these compounds in definite positions. By NMR-[nuclear magnetic resonance] measurements the hydrogen atoms which could be introduced, are shown not to undergo exchange reactions.