Experimental Atherosclerosis in Autogenous Venous Grafts

Abstract

In this experimental study, autogenous venous grafts implanted in the aorta and iliac and femoral arteries of dogs with hypercholesterolemia, induced by a standardized atherogenic regimen, developed diffusely severe atheroma and appeared to be even more susceptible to atheroma than autogenous aortic grafts, Dacron tubes, or the undisturbed arteries of the host.