Chromosome sublocalization of a cDNA for human DNA polymerase-β to 8p11→p12
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 47 (3), 121-124
- https://doi.org/10.1159/000132527
Abstract
We have localized a cDNA fragment that codes for human DNA polymerase-β. Using somatic cell and in situ hybridization techniques, this cDNA was cloned by screening a human KM-3 cell cDNA library in λgt 11 for expression of fused β-galactosidase-human DNA polymerase-β proteins. We have mapped this human polymerase-β gene to the short arm of chromosome 8 in the subregion 8p11→p12.Keywords
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