Prediction of prolonged ventilator dependence in children by respiratory function measurements
- 1 January 1999
- journal article
- Published by IOP Publishing in Physiological Measurement
- Vol. 20 (2), 201-205
- https://doi.org/10.1088/0967-3334/20/2/309
Abstract
Complications of ventilatory support are more common if this assistance is prolonged. Our aim was to determine if results of respiratory function measurement on the first day of ventilation identified children who would develop prolonged ventilatory dependence (4 days) and whether such results were a more accurate predictor than readily available clinical data. Thirty three children, median age 2 years (range 0.1-13.6), who were supported by a constant flow ventilator and hence had measurements of compliance of the respiratory system (CRS) and resistance of the respiratory system (RRS) on the first day of ventilatory support, were retrospectively identified. Those who needed prolonged ventilatory support had a lower CRS on day one (ppp2O) had similar sensitivities (83%) and specificities (71% and 67% respectively) in predicting prolonged ventilatory dependence. The CRS results, unlike the maximum PIP results, however, were always available on the first day of ventilatory support. We therefore conclude that respiratory function measurements have a role in identifying children who would benefit from strategies to prevent prolonged ventilator dependence.Keywords
This publication has 16 references indexed in Scilit:
- Manoeuvres to elevate mean airway pressure, effects on blood gases and lung function in children with and without pulmonary pathologyEuropean Journal of Pediatrics, 1998
- Lung volume measurements immediately after extubation by prediction of “extubation failure” in premature infantsPediatric Pulmonology, 1996
- Statistics Notes: Diagnostic tests 3: receiver operating characteristic plotsBMJ, 1994
- Effect of positive end expiratory pressure and mean airway pressure on respiratory compliance and gas exchange in children with liver diseaseEuropean Journal of Pediatrics, 1994
- The effects of bedside pulmonary mechanics testing during infant mechanical ventilation: A retrospective analysisPediatric Pulmonology, 1993
- Measurements of pulmonary mechanics prior to the elective extubation of neonatesPediatric Pulmonology, 1990
- Comparison of dynamic and static measurements of respiratory mechanics in infantsThe Journal of Pediatrics, 1989
- Respiratory mechanics in mechanically ventilated patients with respiratory failureJournal of Applied Physiology, 1985
- The meaning and use of the area under a receiver operating characteristic (ROC) curve.Radiology, 1982
- Successful extubation of neonatesCritical Care Medicine, 1981