Our purpose in this report is to acquaint the medical profession with the results obtained in the treatment of 1,000 cases of various infections with streptomycin. This study was carried out by fifty-five investigators1accredited to the Committee on Chemotherapeutic and Other Agents of the National Research Council; in addition, many individual physicians cooperated with the Committee by reporting the results of treatment with streptomycin.2 The discussion of these cases will be concerned with overall results in various groups of cases. Separate and detailed reports will be made by individual investigators in due course of time. The streptomycin used in this study was provided by the National Research Council from supplies allocated to it by the Civilian Production Administration for clinical investigations recommended by the Committee. The costs of the streptomycin were covered by grants-in-aid to the National Research Council from eleven pharmaceutical and chemical companies.3 SELECTION