RHODE ISLAND DERMATOLOGICAL SOCIETY

Abstract
Melanomata Pathologically Malignant, Clinically Nonmalignant, in a Case of Xeroderma Pigmentosum. Presented by Dr. F. Ronchese, Providence. A woman aged 35, with xeroderma pigmentosum since the age of 2 years, was the subject of a paper presented at a meeting of the New England Cancer Society, in Providence, Nov. 6, 1946 (Rhode Island M. J.30:225 [April] 1947). The areas chiefly involved are, as usual, the exposed ones—the face, neck, upper portion of the chest, arms, and, lower legs. The condition, which has become progressively worse in the last 20 years, has nonetheless not prevented normal housework on a farm and marriage, five years ago, thus far childless. An older sister, living in a neighboring city, has a milder form of xeroderma pigmentosum, but with the same pattern of spotty hyperpigmentation on the exposed parts. Many of the lesions were widely surgically excised and diagnosed as malignant