A total of 218 fetal transfusions were carried out on 100 fetuses in a 55-month period. The survival rate improved from 28% (11 of 39) in the first 22 months to 62% (38 of 61) in the last 33 months. Failure to reduce the incidence of hydrops fetalis is due to failure to refer sensitized women for investigation sufficiently early in gestation. Administration of digoxin to the hydropic fetus and digoxin and diuretics to the mother may have accounted for the survival of six hydropic fetuses in the last 33-month period. Fetal transfusions are undertaken if serial amniotic fluid optical density rise measurements show an increase into the top four fifths of zone 2 of Liley. Fetal salvage, in Winnipeg, is satisfactory when fetal transfusions are begun early. Two thirds of all fetuses initially transfused before 26 weeks gestation now survive.