ESTEROLYTIC ACTIVITY OF ELASTASE

Abstract
The esters of L-alanine were found to be excellent substrates for elastase. The pH-dependence study using two methyl esters of this substrate showed the participation in the mechanism of an ionizing group with an apparent pK of 6.85 and a decrease of the activity at pH's greater than 10 (that could correspond to an apparent pK of 11.4).
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