Investigations on the Influence of Prolactin Suppression on Reproductive Function in Bulls
- 24 April 2009
- journal article
- Published by Hindawi Limited in Andrologia
- Vol. 11 (1), 1-10
- https://doi.org/10.1111/j.1439-0272.1979.tb02149.x
Abstract
In 3 mature bulls 2 injections (i.m.) of 150 mg 2-Br-alpha-ergocryptine (CB-154, Sandoz) within 48 hrs. decreased the plasma prolactin concentrations significantly for about 14 days (first experiment). In a second experiment, where treatment was repeated after 2 weeks, the period of maximal prolaction deficiency could be extended to a length of about 4 weeks. However, intensity of prolactin inhibition was less pronounced. This is attributed to seasonal factors. Neither during the shorter nor during the longer period of prolactin suppression were apparent changes of the LH and testosterone levels observed. Apart from a minor increase in the rate of morphologically abnormal sperm cells, reproductive function as libido, mating behaviour, semen quality, secretory activity of the accessory glands (concentration of fructose, GPC and chloride in seminal plasma and pre-sperm fraction resp.) were not significantly affected. It seems questionable, therefore, whether under physiological conditions prolactin is essential for the regulation of sexual functions in mature bulls.Keywords
This publication has 31 references indexed in Scilit:
- Effect of prolactin and growth hormone on prolactin and LH receptors in the dwarf mouseReproduction, 1976
- Biology of prolactinPharmacology & Therapeutics. Part B: General and Systematic Pharmacology, 1975
- Effects of Inhibitors of Pituitary Prolactin Release on Testicular Cholesterol Stores, Seminal Vesicles Weight, Fertility, and Lactation in Mice1Biology of Reproduction, 1974
- Galactorrhoea: Successful Treatment with Reduction of Plasma Prolactin Levels by Brom-ergocryptineBMJ, 1972
- EFFECTS OF PROLACTIN AND LUTEINIZING HORMONE ON THE CHOLESTEROL STORES IN THE MOUSE TESTISJournal of Endocrinology, 1971
- EFFECTS OF PROLACTIN ON SPERMATOGENESIS IN HYPOPHYSECTOMIZED MICEJournal of Endocrinology, 1971
- Serum Prolactin Levels in Rats During Different Reproductive StatesEndocrinology, 1970
- THE INFLUENCE OF PITUITARY HOMOGRAFTS ON THE WEIGHT OF THE ACCESSORY REPRODUCTIVE ORGANS IN CASTRATED MALE MICE AND RATS AND ON MATING BEHAVIOUR IN MALE MICEJournal of Endocrinology, 1970
- INFLUENCE OF PITUITARY HOMOGRAFTS ON THE WEIGHT OF SEMINAL VESICLES IN CASTRATED MICEJournal of Endocrinology, 1967
- INFLUENCE OF PROLACTIN ON MALE FERTILITY IN DWARF MICEJournal of Endocrinology, 1966