Induction of the bovine trypsinogen—trypsin transition by peptides sequentially similar to the N‐terminus of trypsin
Open Access
- 19 October 1976
- journal article
- Published by Wiley in FEBS Letters
- Vol. 68 (2), 231-236
- https://doi.org/10.1016/0014-5793(76)80443-7
Abstract
A technique using commercially available B-mode gray scale ultrasonography for imaging the head in the newborn and young infant is described. Serial scans were performed at several angles from the canthomeatal line. Images of technical quality previously unobtainable are shown. Normal anatomic structures such as ventricles, cerebral peduncles, pons, cerebellum, sulci, gyri, choroid plexus, falx cerebri, and tentorium cerebelli can be demonstrated. From April 1978 through December 1978, 165 gray scale ultrasonograms of the head on 111 children younger than 2 years were performed; 63 normal and 48 abnormal patients were studied, with hydrocephalus of various etiologies the most common abnormality. Porencephalic cysts, developmental anomalies, intraventricular and intracerebral hemorrhages, cephalohematoma, subdural hematomas, and arteriovenous malformations were demonstrated. Because of its safety and relatively low cost, ultrasonography proved to be an excellent method for following ventricular size and shunt function.Keywords
This publication has 30 references indexed in Scilit:
- The phylogeny of trypsin-related serine proteases and their zymogens. New methods for the investigation of distant evolutionary relationshipsJournal of Molecular Biology, 1975
- Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitorJournal of Molecular Biology, 1974
- Inactivation of trypsinogen by methane sulfonyl fluorideFEBS Letters, 1974
- Catalysis by chymotrypsinogen. Demonstration of an acyl-zymogen intermediateBiochemistry, 1974
- The structure of bovine trypsin : Electron density maps of the inhibited enzyme at 5 Å and at 2·7 Å resolutionJournal of Molecular Biology, 1974
- A STUDY OF THE ACTIVE CENTER OF TRYPSINOGEN BY COMPARATIVE AFFINITY CHROMATOGRAPHY OF TRYPSINOGEN, α‐, β‐, ψ‐TRYPSINS, DIP‐TRYPSIN, CHYMOTRYPSINOGEN, α‐CHYMOTRYPSIN AND ELASTASEInternational Journal of Peptide and Protein Research, 1974
- Relation of the α-amino group of trypsin to enzyme function and zymogen activationBiochemistry, 1973
- Interaction of basic pancreatic trypsin inhibitor with trypsinogenFEBS Letters, 1969
- Structure of crystalline α-chymotrypsinJournal of Molecular Biology, 1968
- p-Nitrophenyl-p′-guanidinobenzoate HCl: A new active site titrant for trypsinBiochemical and Biophysical Research Communications, 1967