Simple fluorimetric screening for carazolol in swine kidneys bij means of Sep‐Pak cartridges
Open Access
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Veterinary Quarterly
- Vol. 7 (1), 73-76
- https://doi.org/10.1080/01652176.1985.9693957
Abstract
A simple method to determine the B‐blocker carazolol in swine kidneys is presented. Spiked samples, homogenised under alkaline conditions, were heated. Passage of the ether extracts through C18 and silica Sep‐Pak cartridges yielded a fraction containing the carazolol in 88% recovery. In this fraction carazolol was determined by fluorescence spectrophotometry. By this method a level of 1 μg/kg in spiked samples can be detected. Injection of 10 μg/kg body weight, 105 minutes before slaughter, resulted in carazolol contents in kidneys ranging from 1110 25 μg/kg (n = 8).Keywords
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