Reliability of bioelectrical impedance methods in detecting body fluids in elderly patients with congestive heart failure
- 1 January 2006
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 66 (1), 19-30
- https://doi.org/10.1080/00365510500402158
Abstract
Objective. To investigate the reliability of bioelectrical impedance analysis (BIA) in estimating total body water (TBW) and extracellular water (ECW) in elderly patients suffering from congestive heart failure (CHF). Material and methods. In 72 elderly subjects, 34 with CHF (aged 83.9±6.9 years) and 38 healthy controls (78.7±7.5 years), TBW and ECW values were assessed using dilution methods, and bioelectrical variables were measured using single frequency BIA (SF‐BIA) at 1 and 50 kHz, and bioelectrical spectroscopy (BIS). Results. In CHF patients, Ht2/R1 correlated weakly with TBW (r = 0.56) and ECW (0.47). In both healthy controls and CHF patients, TBW correlated strongly with Ht2/R50, Ht2/R0, Ht2/R∞ and Ht2/Zc. Using multiple regression analysis and the Bland–Altmann approach, SF‐BIA at 50 kHz and BIS proved similar in predicting TBW for both the explained variance (R2∼0.89) and the limits of agreement. In all subjects, ECW was estimated best by including height, weight and Ht2/R0 (R2 0.75) or Ht2/Zc (R2 0.77) in multivariate models, while SF‐BIA at 50 kHz did not explain more than 71 % of ECW variability. The SEE % was nonetheless about twice the SEE % for estimating TBW. Conclusions. SF‐BIA at 1 kHz is unreliable in predicting body fluids in elderly people with CHF. SF‐BIA at 50 kHz and BIS are useful for estimating TBW in healthy elderly people and in cases of water imbalance, but both methods are less reliable in estimating ECW, particularly in conditions of fluid overload.Keywords
This publication has 30 references indexed in Scilit:
- Diagnosis and management of heart failure: implications of the recent European Society of Cardiology Guidelines for the older patientAge and Ageing, 2003
- Total body water and extracellular water measurements throughin vivodilution of D2O and bromide as tracersJournal of Spectroscopy, 2003
- Congestive Heart Failure in the CommunityCirculation, 1998
- Validation of Multi‐Frequency Bioelectrical Impedance Analysis in Detecting Changes in Fluid Balance of Geriatric PatientsJournal of the American Geriatrics Society, 1997
- Measurements of total body and extracellular water in cirrhotic patients with and without ascitesHepatology, 1991
- Estimation of extracellular and total body water by multiple-frequency bioelectrical-impedance measurementThe American Journal of Clinical Nutrition, 1991
- Methods for the assessment of human body composition: traditional and newThe American Journal of Clinical Nutrition, 1987
- Comparison of oral and intravenous administration of sodium bromide for extracellular water measurementsThe American Journal of Clinical Nutrition, 1987
- Estimation of total body water by bioelectrical impedance analysisThe American Journal of Clinical Nutrition, 1986
- A simple, inexpensive method of determining total body water using a tracer dose of D2O and infrared absorption of biological fluidsThe American Journal of Clinical Nutrition, 1985