Diagnosis of Cerebral Lesions by Thallium 201

Abstract

The diagnostic possibilities of 201Tl in various cerebral lesions were described. Two radiopharmaceuticals were used in 124 patients: 201Tl citrate and 99mTc pertechnetate labeled. When 201Tl was used, all cases of definite cerebral lesion gave a positive result within 10 min of injection. In 85.4% the definition was better, and small metastases which were invisible with 99mTc could be demonstrated. More than 2/3 of the time, neoplastic lesions were better defined and distinguished from adjacent normal areas of hyperactivity. 201Tl promises greater diagnostic usefulness with an examination time of only 30 min.