Mechanisms of Atrial Fibrillation Termination by Pure Sodium Channel Blockade in an Ionically-Realistic Mathematical Model
- 18 March 2005
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 96 (5), e35-47
- https://doi.org/10.1161/01.res.0000160709.49633.2b
Abstract
The mechanisms by which Na+-channel blocking antiarrhythmic drugs terminate atrial fibrillation (AF) remain unclear. Classical “leading-circle” theory suggests that Na+-channel blockade should, if ...Keywords
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